Rapid antigen diagnostics for emerging pathogens

Abstract: A large number of animal species are hosts to viruses in geographic areas that have historically been separated from humans. With climate change, deforestation, and increased urbanization, what was once rare human contact with these pathogens is increasing, leading to spillover events that cause emerging virus infections. Rapid diagnostic tests are needed for population surveillance to identify circulating pathogens, as well as to serve health care workers in detecting and distinguishing pathogens for optimal patient care. The goal of our work is to develop low cost tests that are simple to use, do not require power, and do not require special chemicals. In COVID19 disease, the absence of a vaccine means that active vigilance, accomplished by regular testing (every 2-3 days) is required to prevent superspreader transmission. This regular testing requires an inexpensive test that can be used as a point-of-care diagnostic. We are actively pursuing technologies to reduce the cost of developing rapid antigen tests, permitting advance diagnostics development that precedes outbreaks and epidemics.

BiologyComputer sciencePhysics

Audience: general audience

SENSE.nano Symposium from MIT.nano